• Dissemination of Piscine orthoreovirus-1 (PRV-1) in Atlantic Salmon (Salmo salar) during the Early and Regenerating Phases of Infection 

      Dhamotharan, Kannimuthu; Bjørgen, Håvard; Malik, Muhammad Salman; Nyman, Ingvild Berg; Markussen, Turhan Ali Dadasbilge; Dahle, Maria; Koppang, Erling Olaf; Wessel, Øystein; Rimstad, Espen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-20)
      <i>Piscine orthoreovirus-1</i> (PRV-1) can cause heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (<i>Salmo salar</i>), but the line of events from infection, pathologic change, and regeneration has not been thoroughly described. In this study, the cellular localization and variation of PRV-1 RNA and protein levels were analyzed at different times post-exposure in experimentally ...